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A new study from Brown University indicates that nicotine is not only addictive, but it may also interfere with dozens of cellular interactions in the body. The study, which is published in the Journal of Proteone Research, shows that nicotine may affect the body more extensively than previously thought. Nicotine appears to impact cell communication throughout the mammalian nervous system, and "opens several new lines of investigation" for possible treatments of smoking addiction and disease.

The study analyzed the cellular processes of brain tissue in mice. In particular, researchers studied a receptor (the alpha-7 receptor) in the brain where nicotine bonds with the surface of the cells when it enters the body. Researchers compared cellular processes in the brains of mice with the receptor and in mice without, and found that 55 different proteins interacted with the alpha-7 receptor. This finding indicates that the alpha-7 receptor may have many more functions in the body than previously known, and that the presence of nicotine may negatively affect each of these functions. (Sources: www.miller-mccune.com)

Labels: addiction, smoking, nicotine

Posted By: Aspen Education Group